Publications
Category: MRI
Validation of IXIQ.Ai+gBSI : an automated framework for caudate atrophy measurement in Huntington’s disease
We have developed a fully automated framework that uses deep learning for caudate segmentation (IXIQ. Ai) and generalised BSI (gBSI) for longitudinal measurements. Here, we validate the new method by comparing its volumetric scores with those of the standard manual pipeline (Man+BSI). Man+BSI produced larger caudate volumes than IXIQ.
Deep-learning methods for enrichment of Alzheimer’s Disease clinical trials using MRI and PET
Drug development trials aimed to halt Alzheimer’s disease (AD) progression favour recruitment of participants at early stages, preferably before symptomatic onset. In this investigation, we developed a deep-learning framework to differentiate participants with accelerated cognitive decline from those that remain cognitively stable within 24 months.
9-10 of 10 results