Advancing Amyloid Assessment in PET Imaging: Integrating AI with Quantitative Metrics
Why is amyloid important in Alzheimer’s disease? Amyloid plaque accumulation in the brain is a defining biological feature of Alzheimer’s disease. Accurately identifying whether a person has abnormally high levels of amyloid, or is amyloid-positive, is critical for Alzheimer’s research and clinical trials.
Erosion of The Supratentorial White Matter Reference for Increased Power in Longitudinal Amyloid PET
The use of the supratentorial white matter as a reference region, alone 1 7 or in composite 3 can facilitate the detection of subtle changes in amyloid plaque burden Investigators often erode or otherwise restrict the sWM labels to reduce the influence of signal “spill in” from grey matter 2 4 8 but the optimal extent…
Comparison of amyloid positivity and global cortical SUVR between black and white non-Hispanic participants in the GAP Bio-Hermes study
Summary: This poster shows our further investigation on the amyloid PET differences between Black and White participants in the GAP Bio-Hermes study and to better understand the relationship between Aβ+ status from visual read and quantitative SUVR.