Accurate detection, segmentation, and quantification of lesion dynamics in longitudinal MRI is crucial for monitoring disease progression in Multiple Sclerosis, and for evaluating the efficacy of therapeutic interventions. We present an efficient, automatic method utilising deep learning to assess lesion changes in FLAIR MRI with a high degree of accuracy.
Summary: We developed and validated scalable and robust methods for automated volumetric analysis of brain white matter hyperintensities (T2 lesions) and regions of interest in multiple sclerosis.