Data Analytics

AI Biomarker Algorithms

highly differentiated algorithms measuring existing and previously inaccessible biomarkers at scale, with high precision

AI-led accurate assessment of brain pathologies and disease-specific symptoms, identifying over 150 brain structures, quantifying the changes in both whole-brain and regional volumes over the time course of a clinical trial.

Validates measures of function and biochemical characteristics across the identified brain regions.

Provides the trial sponsor with information on the impact the pipeline drug is having on disease progression.

Regulatory compliant (GCP and CFR 11)

LEAP methodology

Brain Region Analytics

brain region analysis for a given image, to measure brain volume both cross-sectionally and longitudinally.

Supports critical patient-level decision-making, including providing insights into patient eligibility and drug efficacy.

‘Global’ measurements on the whole brain and ‘regional’ measuring of specific local brain regions

Human-expert-equivalent analysis at a faster pace and with higher levels of consistency and replicability.

Capability to be trained on a specific problem using data for a precise brain region in a particular therapeutic indication

Regulatory compliant (GCP and CFR 11)

differentiated technology4 v2

Highlights

CONSISTENT	delivering advanced clinical endpoints while reducing variability by automating traceability and consistent reproducibility into every dataset, all underpinned by a highly granular audit trial.
COMPATIBLE	reduces data upload, management and analysis burden for sites, sponsors and readers through seamless integration with existing workflows without the need for additional software or tools.
FLEXIBLE	capabilities in all clinical trial phases, including patient stratification and exploratory endpoints, as well as use for post-market assessment and clinical diagnostics.
BESPOKE	distinct technologies and scientific expertise to meet specific neurological disease needs with the required specialism and complex understanding of each different indication.