Erosion of The Supratentorial White Matter Reference for Increased Power in Longitudinal Amyloid PET
The use of the supratentorial white matter as a reference region, alone 1 7 or in composite 3 can facilitate the detection of subtle changes in amyloid plaque burden Investigators often erode or otherwise restrict the sWM labels to reduce the influence of signal “spill in” from grey matter 2 4 8 but the optimal extent…