Neurological Disorders - Harmonisation of Imaging in Clinical Trials

Speakers:

• Helen Crawford, Head of Image Management – IXICO
• Niccolo Fuin, Senior Biomarker Scientist – IXICO

Harmonising imaging and clinical protocols at the start of a multi-centre clinical trial for neurological disorders is a critical challenge. This webinar provides an in-depth overview of these challenges and explores effective strategies for integrating imaging biomarkers into clinical trials.

What You’ll Learn:

Imaging Protocol Considerations:

• Understand the significance of harmonisation for enhancing measurement precision in clinical trials.
• Explore challenges in adapting imaging and clinical protocols across various scanner platforms and therapeutic areas.

Imaging Harmonisation Strategies:

• Discover the importance of consistency across trial sites through standardisation and quality control measures.
• Learn about the role of academic and industry consortia in validating imaging biomarkers.

Case Studies and Integration:

• Examine practical examples of harmonisation in MRI and PET imaging.
• Identify common pitfalls and lessons learned from both large-scale and small-scale harmonisation efforts

Holistic Key Considerations:

• Gain a comprehensive view of essential factors for harmonising imaging and clinical protocols.
• Review real-world examples that illustrate how to maintain uniformity and address challenges effectively.

Join experts Helen Crawford and Niccolo Fuin as they guide you through these essential topics, offering their extensive knowledge and answering your questions. This webinar is a unique opportunity to enhance your understanding of multi-centre imaging harmonisation, ensure the success of your clinical trials.

About the speakers

Niccolo Fuin, Senior Biomarker Scientist - IXICO

Niccolo Fuin is an expert in neuroimaging acquisition and biomarker science, currently a Senior Biomarker Scientist at IXICO. He holds a PhD in Medical Physics applied to Nuclear Medicine from University College London. He has over a decade of academic experience through his work as a researcher at University College London, MGH/Harvard Medical School and Kings’ College London, where he has published numerous research papers on MRI and PET imaging acquisition.

Niccolo’s career spans both academic and clinical trial settings. He has collaborated with various biopharmaceutical companies and research institutions to advance the use of imaging biomarkers in clinical trials. He has been involved in developing guidelines for harmonizing MRI data acquisition and has shared his expertise at international conferences, focusing on imaging protocol design and biomarker integration. His efforts have been instrumental in supporting the development of effective treatments for neurological conditions.

Helen Crawford, Head of Image Management - IXICO
Helen Crawford is an expert in neuroimaging and clinical trials, currently the Head of Image Management at IXICO. She holds a PhD in Clinical Neuroscience from University College London (UCL) and has over 15 years of experience in the field of neurology.

Helen oversees the overall coordination and management of all activities required to qualify, receive and analyse data for IXICO’s portfolio of clinical trials from start-up through to close-out. Helen’s clinical neuroscience background and significant operational clinical trials experience ensure that her site qualification team apply the leading principles of image harmonisation in clinical trials.  This includes both advice, consultancy, and input into sponsor trial protocols and the practical and critical task of supporting imaging sites in their scanner setup.

 

 

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