This comprehensive overview of the roles of structural, functional, and diffusion MRI, PET, MRS, and MEG serves as a resource for effectively integrating neuroimaging methodologies into the design and execution of Huntington's disease clinical trials.

The paper discusses their applications in patient selection, safety monitoring, and demonstrating efficacy. It additionally addresses challenges in translation to trial settings, including equipment requirements, standardization, patient burden, and data interpretation.

Links to where to access this research article:

• Neuroimaging to Facilitate Clinical Trials in Huntington’s Disease: Current Opinion from the EHDN Imaging Working Group - IOS Press

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