IXICO plc (AIM: IXI), is a global leader in neuroscience imaging and biomarker analytics, using its proprietary AI-driven platform to help advance the treatment of neurological disorders and reduce the uncertainties associated with drug discovery, development and monitoring. As a key part of the global neurological disease research community, the Company has built a global reputation and 20-year track record as an end-to-end Imaging Contract Research Organisation (iCRO) working with leading pharma companies, innovative biotech's, disease consortia and non-profit organisations. IXICO has supported hundreds of neurological clinical trials, analysed hundreds of thousands scans and built an expansive network of expert imaging centres around the world.
The IXICO Platform is tailor-made for neurological disease, reliably processing data from global trials, precisely measuring key imaging biomarkers associated with the identification, progression and treatment of diseases such as Alzheimer's, Huntington's and Parkinson's. Image data is interrogated by the Platform and IXICO's expert scientists translating complex data into clinically meaningful while minimizing data variability and increasing reproducibility.
Our people are empowered to enable us to achieve our company goals and their own personal development through the “4A” values at the heart of our culture: Aspiration, Ability, Agility and Accountability.
To help us deliver our medical image analysis solutions to large clinical trials we are hiring a dedicated Director, Neuroscience Medical Affairs on a permanent full-time capacity.
Purpose of the Role:
The Director, Neuroscience Medical Affairs is a senior medical-scientific lead, reporting directly to the CSO/CMO. The role holder leads priority Key Opinion Leader (KOL) relationships, provides senior scientific input to pharma engagements and partnerships, drives the company's publication and congress activity, and contributes medical input to IXICO's growing portfolio of regulated software products. The role spans IXICO's full therapeutic-area scope (AD, PD, HD and selected rare neurological indications) and reflects the company's evolving scientific positioning, including the increasing relevance of multimodal biomarker integration as the diagnostic and treatment landscape evolves. The role is hands-on and externally visible: the post holder is expected to be a credible scientific voice for IXICO with pharma sponsors, KOLs, consortia and clinical networks.
Essential Duties and Responsibilities:
Medical Affairs strategy and planning
- Working closely with the CSO/CMO, support development of the Medical Affairs strategy and lead translation into an actionable annual operating plan covering KOL engagement, publications, congresses, consortium activity and pharma scientific engagement.
- Own end-to-end delivery of priority workstreams against this plan, with clear KPIs and reporting cadence.
- Identify and surface emerging scientific and competitive developments that may inform updates to the strategy, including evolutions in the diagnostic frameworks, the multimodal biomarker landscape, treatment mechanisms, and the regulated software product space.
KOL and clinical-network engagement
- Lead day-to-day engagement with priority KOLs across AD, PD, HD and selected rare neurological indications.
- Maintain and grow relationships with consortium partners and Scientific Advisory Board members.
- Build relationships into neurologist, memory-clinic and diagnostic-imaging-network communities to understand evolving requirements for clinical decision support tools.
Publications, congresses and external scientific communication
- Drive IXICO's peer-reviewed publication output across priority scientific themes.
- Support planning of IXICO's scientific congress presence at major meetings, including abstract submissions, presentations, KOL meetings and pharma engagement.
- Support development and review of external scientific material (e.g. webinars, white papers, blog posts, website content), assuring scientific accuracy and alignment with the agreed commercial and scientific positioning.
Pharma sponsor and partner medical engagement
- Provide medical support to Business Development, including bid defences, capability presentations and scientific advisory interactions with pharma sponsors.
- Act as a scientific point of contact in strategic partnerships, supporting joint scientific narratives, co-publications and co-developed evidence packages where appropriate.
- Provide medical input into proposals, statements of work and study imaging charters where senior medical-affairs perspective is needed.
Medical input to products and regulatory submissions
- Contribute medical and clinical-scientific input to IXICO's SaMD and analytics product roadmap, including intended-use definition, claim-specific validation considerations and the clinical-evidence narrative for products.
- Partner with Regulatory Affairs and R&D on the medical content of pre-submission and submission packages.
Qualifications and skills required for the role:
Essential
- Medical degree (MD) or PhD in a relevant clinical or neuroscience discipline (e.g. clinical neurology, neuroradiology, dementia medicine, neuroscience).
- Significant senior experience in medical affairs, clinical science or clinical development in CNS therapeutic areas, gained in a CRO, pharma, biotech, medical device, diagnostic or comparable industry environment.
- Demonstrable track record of independent delivery of medical affairs workstreams - KOL relationships built and sustained, peer-reviewed publications co-authored or led, congress activity planned and executed, pharma scientific engagements led.
- Strong working knowledge of the CNS therapeutic and biomarker landscape.
- Good working knowledge of the regulatory landscape for neurological clinical trials and (ideally) SaMD products.
- Established personal credibility with pharma medical and biomarker contacts and with academic KOLs in at least one of IXICO's core therapeutic areas.
- Excellent scientific communication - published in peer-reviewed literature; comfortable delivering invited talks and high-stakes sponsor presentations.
- Strong collaborative working style across Medical Affairs, R&D, Regulatory and Commercial functions.
- Willingness to travel internationally for conferences, KOL meetings, pharma engagements and consortium activity.
Desirable
- Prior medical affairs experience in a CRO, imaging-CRO, medical device or diagnostic company.
- Direct experience supporting SaMD or in vitro diagnostic submissions (intended-use authoring, clinical-evidence packages).
- Existing engagement with relevant consortia.
- Working familiarity with multimodal biomarker integration in CNS clinical trials or diagnostics.
- Knowledge of neurologist-facing clinical decision support workflows in memory clinics, dementia services and diagnostic imaging networks.
Benefits:
- Competitive remuneration package including benchmarked salaries.
- Staff Annual Bonus Plans and Annual Salary Review.
- Generous employer pension contribution of 6%.
- 25 days annual leave, increasing up to 28 days with every year at IXICO.
- BUPA private medical insurance scheme.
- Life Assurance of 4x annual salary.
- Employee Benefits Portal, offering various discounts in retail, food & drink, and entertainment.
- Engaging and social environment, with fundraising and sporting activities and seasonal events such as Summer and Christmas parties.
- Wellbeing initiatives such as eye tests, flu jabs, and Mental Health Awareness Training.
- Employee Assistance Programme offering advice and support on a wide range of topics.
- Hybrid working model pattern split between working in the City of London and remotely.
- Reimbursement allowance to purchase equipment to support working from home.
- Generous employee referral scheme offering £2,000 for referring a successful candidate to the company.
- Financial assistance for professional qualifications.
- Opportunity to contribute to an industry where your work has an impact every single day.
How to Apply
IXICO is working hard to create a representative, inclusive and empowered team, because we believe different experiences, perspectives and backgrounds make a better workplace, and ultimately better services.
IXICO doesn’t discriminate on the basis of race, colour, religion or belief, gender, national origin, age, sexual orientation, marital status, disability or any other protected class.
This is a great opportunity for a motivated Director, Neuroscience Medical Affairs in a permanent full-time capacity to thrive in an engaging and fast-paced environment, to make a difference on an everyday basis.
If you think IXICO should meet you, please send us your CV and covering letter by email to careers@ixico.com or apply directly via LinkedIn. We are looking forward to your application.
Please note that our entire business is operating under a Hybrid-Working Model, where UK-based employees are required to attend our London office 2 days a week. If you have got any questions, please reach out to our careers team.
Please note that IXICO will process the data provided by you only in order to perform the outlined recruitment exercise. For more details on what data we process and on what legal basis this happens please view our Recruitment Privacy Policy or contact careers@ixico.com.
