# Alzheimer’s Landscapes: Comorbidities, Novel Targets, and Imaging Through the Neuroradiologist’s Lens 22 Oct 25 webinars # Alzheimer’s Landscapes: Comorbidities, Novel Targets, and Imaging Through the Neuroradiologist’s Lens Alzheimers Disease [ ](https://x.com/intent/tweet?url=https://ixico.com/news-and-resources/webinars/alzheimers-landscapes-comorbidities-novel-targets-and-imaging-through-the-neuroradiologists-lens/) [ ](https://bsky.app/intent/compose?text=https://ixico.com/news-and-resources/webinars/alzheimers-landscapes-comorbidities-novel-targets-and-imaging-through-the-neuroradiologists-lens/) [ ](https://www.facebook.com/sharer/sharer.php?u=https://ixico.com/news-and-resources/webinars/alzheimers-landscapes-comorbidities-novel-targets-and-imaging-through-the-neuroradiologists-lens/) [ ](https://www.linkedin.com/shareArticle?mini=true&url=https://ixico.com/news-and-resources/webinars/alzheimers-landscapes-comorbidities-novel-targets-and-imaging-through-the-neuroradiologists-lens/) [ Play Video ](https://youtube.com/watch?v=yDUshv6gkCU "Play Video") Understanding Alzheimer’s Disease (AD) requires more than just a focus on amyloid and tau. This webinar explores how radiology is uncovering the impact of comorbidities—such as neuroinflammation and cerebrovascular pathology—on AD risk and progression. Join Frederik Barkhof and Alex Henderson as they discuss the evolving role of imaging in clinical trials, emerging therapeutic targets, and the operational realities of implementing advanced imaging strategies. **What You’ll Learn:** - **Comorbidities in AD Progression** Explore how neuroinflammation and vascular pathology interact with core AD mechanisms. - **Imaging in Clinical Trials** Learn how MRI, PET, and quantitative methods are used to identify and monitor biomarkers over time. - **Emerging Therapeutic Targets** Discover new directions in AD treatment beyond amyloid and tau, including APOE4 and targeted brain delivery. - **Radiology in Practice** Hear how imaging protocols are being adapted and standardized to support trial success and cross-site consistency. - **Collaboration & Infrastructure** Understand the importance of cross-disciplinary teamwork and investment in imaging infrastructure. ## About the speakers and moderator **[Frederik Barkhof](https://www.linkedin.com/in/frederik-barkhof-22b2a020a/) - Professor of Neuroradiology, Amsterdam UMC and UCL** Frederik Barkhof is Professor of Neuroradiology at Amsterdam UMC (NL) and at UCL in London (UK). His research interests focus on multiple sclerosis (spinal cord MRI, grey matter, atrophy), ageing (white matter lesions, microbleeds) and dementia (structural, functional, molecular MR and PET). He has (co)authored >1000 papers referenced in PubMed and is listed among 3000 most influential scientists world-wide by Thompson-Reuters. He is the author of the books “Neuroimaging in Dementia” and “Clinical Neuroradiology: the ESNR textbook” of the normal human brain and on movement disorders. He has contributed to the understanding of the functional anatomy of the basal ganglia using fMRI and the diffusion tensor. **[Alexandra Henderson](https://www.linkedin.com/in/alexandra-henderson-1a2180174/), Radiology Manager - IXICO** Alexandra Henderson, MSc, is Radiology Manager at IXICO. She holds an MSc in Clinical Neuroscience from University College London and a BSc in Biomedical Sciences from Northumbria University. At IXICO, Alex manages the radiology operations in clinical trials, including Alzheimer’s disease, focusing on PET and MRI read form and paradigm development, operational reader management, and reporting quality. Her work bridges operations and radiology, supporting the integration of image interpretation into clinical trial workflows. **Moderator: [Kirsi Kinnunen](https://www.linkedin.com/in/kkirsimaria/), Principal Biomarker Scientist – IXICO** Kirsi is a Senior Clinical Neuroscientist (PhD) and Chartered Psychologist with 15+ years of clinical neuroscience research experience. She focuses on brain imaging in CNS clinical trials, with expertise in Alzheimer's, Parkinsonian syndromes, Huntington's, multiple sclerosis, spinocerebellar ataxia, and traumatic brain injury. Kirsi provides science input and imaging planning help for biotechs during the development and maintenance stages of clinical trials.  **This webinar concluded October 22nd 2025** [ Back to Webinars ](/news-and-resources/webinars/) ### Recents ![Where Vascular Disease and Alzheimer’s Meet: Shared Pathways to Cognitive Decline ](/assets/blog-images/AD-Webinar-2026-1__ScaleMaxWidthWzgwMF0_FillMaxWzgwMCw0NTBd_ExtRewriteWyJwbmciLCJ3ZWJwIl0.webp) 1 Oct 26 webinars [Where Vascular Disease and Alzheimer’s Meet: Shared Pathways to Cognitive Decline ](/news-and-resources/webinars/where-vascular-disease-and-alzheimers-meet-shared-pathways-to-cognitive-decline/) [Understanding Imaging in Parkinson’s Disease Trials: From Eligibility to Efficacy](/news-and-resources/webinars/understanding-imaging-in-parkinsons-disease-trials-from-eligibility-to-efficacy/) [Endpoint selection in Huntington’s disease trials: how neuroimaging advances drive better outcomes](/news-and-resources/webinars/endpoint-selection-in-huntingtons-disease-clinical-trials-and-how-advances-in-neuroimaging-can-drive-better-trial-outcomes/) [ Advancing AD Clinical Trials Through Blood-Based Biomarkers & Amyloid PET Webinar](/news-and-resources/webinars/advancing-ad-clinical-trials-through-blood-based-biomarkers-and-amyloid-pet-webinar/) [Parkinson's Disease: Unveiling the Promise of Neuromelanin Sensitive Imaging](/news-and-resources/webinars/parkinsons-disease-unveiling-the-promise-of-neuromelanin-sensitive-imaging/) ### Library [November 2026](/news-and-resources/webinars/archive/2026/11/) [October 2026](/news-and-resources/webinars/archive/2026/10/) [September 2026](/news-and-resources/webinars/archive/2026/09/) [July 2026](/news-and-resources/webinars/archive/2026/07/) [June 2026](/news-and-resources/webinars/archive/2026/06/) [May 2026](/news-and-resources/webinars/archive/2026/05/) [April 2026](/news-and-resources/webinars/archive/2026/04/) [March 2026](/news-and-resources/webinars/archive/2026/03/) [February 2026](/news-and-resources/webinars/archive/2026/02/) [January 2026](/news-and-resources/webinars/archive/2026/01/) [2025](/news-and-resources/webinars/archive/2025/) [2024](/news-and-resources/webinars/archive/2024/) [2023](/news-and-resources/webinars/archive/2023/) [2022](/news-and-resources/webinars/archive/2022/) [2021](/news-and-resources/webinars/archive/2021/) [2020](/news-and-resources/webinars/archive/2020/) [2019](/news-and-resources/webinars/archive/2019/)