IXICO chosen for new Phase II Alzheimer’s disease study

IXICO plc, the AI data analytics company delivering insights in neuroscience, announces that it has been selected by a current mid-sized biopharmaceutical client to support the company’s Phase II Alzheimer’s disease clinical trial. Conducted across 125 sites in 10 countries over 5 years, the study will investigate an anti-Tau antibody treatment for individuals with prodromal and mild Alzheimer’s disease (AD).  For the study, IXICO will provide advanced neuroimaging solutions involving structural magnetic resonance imaging (MRI), volumetric MRI (vMRI), diffusion MRI (dMRI) and arterial spin labelling (ASL).

AD affects approximately 50 million people worldwide with no available therapies to address the underlying disease pathology. Biopharmaceutical companies are responding to this challenge with innovations in clinical trials and treatment targets in their AD pipelines. These include increased diversification of drug candidates by investigating disease-modifying agents targeting pathways other than the historical focus area of amyloid. This new study, which follows on from the AD study award by Cyclerion Therapeutics, Inc announced on 2 March 2021, further demonstrates the important growing industry trend of target diversification in AD drug development.  

Lammert Albers, Chief Commercial Officer of IXICO, commented:

"IXICO is delighted to be awarded the contract for this new Alzheimer’s disease clinical trial. With less well-defined target biology, limited availability of biomarkers and higher risk of failure, drug development in Alzheimer’s disease presents significant challenges for the industry. In turn, biopharmaceutical sponsors are responding with more disease-modifying treatment candidates and greater diversity of drug targets in AD pipelines.  We are proud to support sponsors in their tireless efforts to bring potential treatments for this devastating disease, and these recent awards reflect the confidence clients place in IXICO as the trusted neuroimaging partner for their Alzheimer’s disease pipeline innovations.”


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Alice Woodings



Date: 10/03/2021